Wednesday, September 14, 2016

Targretin Gel


Targretin Gel is a brand name of bexarotene topical, approved by the FDA in the following formulation(s):


TARGRETIN (bexarotene - gel; topical)



  • Manufacturer: EISAI INC

    Approval date: June 28, 2000

    Strength(s): 1% [RLD]

Has a generic version of Targretin Gel been approved?


No. There is currently no therapeutically equivalent version of Targretin Gel available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Targretin Gel. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors
    Patent 5,780,676
    Issued: July 14, 1998
    Inventor(s): Boehm; Marcus F. & Heyman; Richard A. & Zhi; Lin & Hwang; Chan Kou & White; Steve & Nadzan; Alex
    Assignee(s): Ligand Pharmaceuticals Incorporated
    Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and poiyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
    Patent expiration dates:

    • July 14, 2015
      ✓ 
      Patent use: TOPICAL TREATMENT OF CUTANEOUS LESIONS IN PATIENTS WITH CUTANEOUS T-CELL LYMPHOMA (STAGE IA AND IB) WHO HAVE REFRACTORY OR PERSISTENT DISEASE AFTER OTHER THERAPIES OR WHO HAVE NOT TOLERATED OTHER THERAPIES




  • Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
    Patent 5,962,731
    Issued: October 5, 1999
    Inventor(s): Boehm; Marcus F. & Heyman; Richard A.
    Assignee(s): Ligand Pharmaceuticals Incorporated
    Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
    Patent expiration dates:

    • October 5, 2016




  • Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
    Patent 6,043,279
    Issued: March 28, 2000
    Inventor(s): Boehm; Marcus F. & Heyman; Richard A.
    Assignee(s): Ligand Pharmaceuticals, Incorporated
    Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
    Patent expiration dates:

    • April 22, 2012
      ✓ 
      Patent use: TOPICAL TREATMENT OF CUTANEOUS LESIONS IN PATIENTS WITH CUTANEOUS T-CELL LYMPHOMA (STAGE IA AND IB) WHO HAVE REFRACTORY OR PERSISTENT DISEASE AFTER OTHER THERAPIES OR WHO HAVE NOT TOLERATED OTHER THERAPIES




  • Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
    Patent 6,320,074
    Issued: November 20, 2001
    Inventor(s): Boehm; Marcus F. & Heyman; Richard A. & Zhi; Lin & Koch; Stacie Canan
    Assignee(s): Ligand Pharmaceuticals Incorporated
    Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
    Patent expiration dates:

    • April 22, 2012
      ✓ 
      Patent use: TOPICAL TREATMENT OF CUTANEOUS LESIONS IN PATIENTS WITH CUTANEOUS T-CELL LYMPHOMA (STAGE IA AND IB) WHO HAVE REFRACTORY OR PERSISTENT DISEASE AFTER OTHER THERAPIES OR WHO HAVE NOT TOLERATED OTHER THERAPIES
      ✓ 
      Drug substance




  • Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
    Patent 7,655,699
    Issued: February 2, 2010
    Inventor(s): Boehm; Marcus F. & Heyman; Richard A.
    Assignee(s): Eisai Inc.
    Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and polyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
    Patent expiration dates:

    • April 22, 2012
      ✓ 
      Patent use: TOPICAL TREATMENT OF CUTANEOUS LESIONS IN PATIENTS WITH CUTANEOUS T-CELL LYMPHOMA (STAGE IA AND IB) WHO HAVE REFRACTORY OR PERSISTENT DISEASE AFTER OTHER THERAPIES OR WHO HAVE NOT TOLERATED OTHER THERAPIES
      ✓ 
      Drug substance
      ✓ 
      Drug product



See also...

  • Targretin Gel Consumer Information (Wolters Kluwer)
  • Targretin Topical Consumer Information (Cerner Multum)
  • Targretin Topical Advanced Consumer Information (Micromedex)
  • Targretin topical AHFS DI Monographs (ASHP)
  • Bexarotene Gel Consumer Information (Wolters Kluwer)
  • Bexarotene topical Consumer Information (Cerner Multum)
  • Bexarotene Topical Advanced Consumer Information (Micromedex)
  • Bexarotene topical AHFS DI Monographs (ASHP)

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